List and sedating antihistamines
It is used for general allergic symptoms and is found over the counter in many countries.
Additionally, it functions as a serotonin and norepinephrine reuptake inhibitor, giving it antidepressant properties. It also potentiates the effects of opioid pain medication so less pain medication can be used.
Either H1 or H2 histamine receptors can be blocked by medicines, but the group commonly known as antihistamines blocks the H1 receptor.
They have a number of uses, but are most often used to treat allergies.
It is sometimes combined with hydrocortisone and sold as a cream or gel. Benztropine, also called benzatropine, is a first generation H1 antagonist. It also acts as a dopamine reuptake inhibitor, which can be helpful in treating narcolepsy and attention disorders, and a functional inhibitor of acid sphingomyelinase, which is sometimes used to treat depression.